Controlling the COX-2 Enzyme Can Reduce or Eliminate Pain After Surgery?

Pain from surgery can be minimized with natural options.

My wife had major surgery five days ago. She remained overnight and came home on Wednesday afternoon. She followed all the pre-op instructions about eating, clear liquids, and more before surgery. However, she also started taking whole fruit mangosteen juice and turmeric with piperine several days before surgery and immediately after recovery.

Why is this important? Because controlling the COX-2 enzyme can reduce or eliminate pain. She came home from the hospital without pain and could move around well. A day later, she walked a half-mile with me in the park. She sleeps exceptionally well and never complains about pain, even from a three-hour surgery.

Inflammation Inflammation in the body is normal. Except for the lymph and thymus glands, your immune system works at the cellular and sub-cellular levels. The regulation of your immune system is controlled chemically.

All the body’s cells have thousands of receptors on their surfaces, serving as docking points for chemical messengers – inflammatory cytokines. When docked at a receptor, these messengers signal a cell to act or not perform to a specific condition. A single receptor has no impact on the big scheme of things.

When sliced and diced in surgery, anesthesia controls the pre-surgery, surgery, and post-surgery pain. Removing, realigning, and reattaching ligaments can lead to post-operative pain when the anesthesia wears off. However, if planned correctly, the receptor cells in those parts of your body can be stimulated not to start the internal processes leading to pain, swelling, limited movement, etc.

Aspirin Aspirin predecessors (willow bark salicylates) have been used for over 2,500 years to treat various inflammatory conditions. At the end of the 19th century, the German chemist, Felix Hoffmann, working for Friedrich Bayer & Co., created aspirin, a pain reliever. Aspirin is the most used non-steroidal anti-inflammatory drug (NSAID). Other NSAIDs include acetaminophen, ibuprofen, naproxen, etc.

NSAIDs The inflammation response mechanism of NSAIDs in the body was determined in the early 1970s. Aspirin, and other NSAIDs, block the cyclooxygenase (COX) enzyme responsible for initiating the inflammatory process.

The COX enzyme controls the production of prostaglandins from arachidonic acid. The prostaglandins are messengers that signal the immune system to start the inflammatory processes.
Blood flow and pressure are increased to the injured site. As a result, blood vessels expand, tissues swell, heat, and redness set in, endothelial cells that line the capillaries shrink, causing spaces between the walls for white blood cells to enter, and pain becomes noticeable.

This is the body’s response to injury, trauma, or surgery, and it protects itself from further infection or damage that bacteria, viruses, or fungi might cause. Aspirin (NSAIDs) inhibit the synthesis of prostaglandins and thereby reduce both pain and inflammation.

COX Enzymes Daniel Simmons (Brigham Young University) discovered two kinds of COX enzymes inhibited by NSAIDs – the COX-1 and COX-2 enzymes. The COX-1 enzyme reacts with arachidonic acid to produce basal prostaglandins, which support healthy kidney function, blood clotting, and stomach functioning.

The COX-2 enzyme reacts with arachidonic acid to produce prostaglandin E2, responsible for the symptoms associated with inflammation. NSAIDs treat both pain and inflammation because COX-2 is activated and COX-1 is inhibited. Potentially, kidney damage, bleeding problems, ulcers, and stomach irritation can occur with the overuse of NSAIDs.

COX-2 Selective Inhibitors In the late 1990s, scientists studied the effects of various drugs on both the COX-1 and COX-2 enzymes. They created a ‘COX-2’ selective inhibitor – Vioxx, Celebrex, and Bextra.

Early NSAIDs were equipotent at inhibiting both COX-1 and COX-2 enzymes. The COX-2 selective inhibitors were 30 to 300 times more potent in inhibiting COX-2 than COX-1 without gastrointestinal irritation.

Celebrex and Vioxx were introduced in 1999 and rapidly became the most frequently prescribed drug in the United States. However, additional side effects have been cataloged regarding the COX-2 inhibitors – primarily Vioxx, which was withdrawn voluntarily from the marketplace due to an increased risk of myocardial infarction and stroke.

Prescription medicines inhibit the COX-2 enzyme more than the COX-1 but still inhibit the COX-1 enzyme. This causes additional and potentially more hazardous side effects.

Scientific research takes many forms – ‘in vitro (laboratory dishes), ‘in-vivo’ (laboratory animals), and clinical studies involving human subjects. Both ‘in vitro’ and ‘in vivo’ studies have been done on various natural products that might inhibit COX-2 and not inhibit COX-1. Very few were found.
My research shows that a specific xanthone, gamma mangostin, in the mangosteen fruit effectively shuts down the COX-2 enzyme without affecting the protective COX-1 enzyme.

Gamma-mangostin Dr. K. Nakatani and others working at the Department of Pharmaceutical Molecular Biology at the Graduate School of Pharmaceutical Sciences at Tohoku University, Sendai, Japan, determined that when gamma-mangostin was present in your body, the production of prostaglandin E2 was blocked – effectively shutting down the inflammatory response of the COX-2 enzyme while having zero effect on the COX-1 enzyme. The first study demonstrated that gamma-mangostin directly and selectively inhibited only the COX-2 enzyme.

Dr. James Duke, a world-famous ethnobotanist, lists many of mangosteen’s (Garcinia Mangostana) benefits. Scientific proof can be found in almost 150 independent published scientific articles. Physicians are starting to replace prescription drugs with whole-fruit mangosteen juice.

Dr. Sam Walters and Dr. J. Fredric Templeman offer their opinions on the efficacy of the whole-fruit mangosteen juice to be equal to or outperform the prescription drugs Valium Xanax, Vicodin, Percocet, Celebrex, Vioxx, Bextra, Ultram, Talwin, Midrin, Fioricet, etc.

Curcumin (Turmeric)
Turmeric is a spice. The yellow color of curry comes from turmeric. The active molecule responsible for its health benefits is called curcumin. However, the bioavailability of curcumin in the body is very low. This bioactivity (getting more usable curcumin into the body) can be increased by 2000% by adding piperine, black pepper extract. It is also best to take turmeric (curcumin) with a meal.

Many studies have proven curcumin acts as a natural anti-inflammatory and antioxidant. It also boosts brain-derived neurotrophic factor (BDNF), which helps support the life of neurons in our brains. Research scientists tell us that curcumin can lower the risk of heart disease, cancer, and Alzheimer’s disease. In addition, it is used to treat arthritis and depression.

COX-1 & COX-2 Arachidonic acid is used to synthesize prostaglandins, lipids that are made at the site of injury or trauma, to control the body’s immune responses. Curcumin inhibits the cyclooxygenase enzymes by inhibiting the phosphorylation process that creates prostaglandins.

Both the COX-2 and COX-1 enzymes are inhibited naturally by curcumin. NSAIDs do the same thing but have side effects. The suppression or inhibition of the COX-1 enzyme approximates the ‘selective inhibition’ seen with the prescription drugs Vioxx, Celebrex, and Bextra without any side effects.


Whole-fruit mangosteen juice is needed because most of the xanthones are in the skin or rind of the fruit. I remember vividly one day crushing my knuckle in the car door when I accidentally closed it. It hurt – a lot! I drank about six ounces (double my normal daily amount) of mangosteen juice within five minutes of the accident.

My finger never had any pain unless I squeezed the crushed area. I had total flexibility and mobility. There was no swelling, redness, or heat. I shut down the COX-2 response before it could activate my normal body processes to treat inflammation. I have heard many similar results, from decades-old back pain to migraines.

My wife’s immediate post-operative time has been with literally zero pain. There are only two incidents that I heard her yelp quickly. One was the first time she sat down in her favorite chair – she plopped rather than gently sat down an hour after coming home from the hospital. That has not happened twice!

The second time was when I misjudged a speed bump in a parking lot, and the car’s sudden motion caused her to let me know that she was aware I went over that bump too quickly. Again, that has not happened since. From a pain perspective, it is like she never had surgery.

Mangosteen juice is a fruit juice. Therefore, it is not medicine and cannot be prescribed. However, before buying a bottle and self-treating, talk over your plan with a knowledgeable medical authority to ensure that other drugs you are taking might not become problems.

Live Longer & Enjoy Life! – Red O’Laughlin –


Are Chickens and Monkeys Dominating the Health Headlines?

Is Monkeypox a serious threat to the world?

“The sky is falling, the sky is falling,” is a famous quote from Chicken Little Story found in the Grimm Brothers fairy tales. Just Mathias Thiele first published it in the Danish Language in the early 1800s. However, folklore has been around for over two dozen centuries.

Hysteria and disaster are here now or rapidly approaching. Our media must keep its audiences in dire peril. We have seen that almost daily for the past two-plus years with the pandemic.

Is Monkeypox even an issue to get a headline like today – WHO: Monkeypox Can Be Contained if We Act Now from the 27MAY22 article,

Monkeypox This virus has been around for years. It was first detected in a human in 1970 in DROC (Democratic Republic of Congo). It is rarely seen outside of Central and West Africa.

The World Health Organization reports nearly 300 confirmed cases worldwide. Typical symptoms include fever, body aches, malaise, muscle pain, and lesions or rashes that can form blisters and scabs. It takes about seven or more days for symptoms from the initial infection. The disease is contagious for the entire time a person has it – from initial contact through scabs are fully healed.

Contact with any contaminated material – clothing, bedding, respiratory droplets, body fluids, etc. is enough to infect. Roughly one in twenty may succumb to this virus.

Monkeypox and the United States Yesterday, the U. S. Centers for Diseases Control and Prevention confirmed nine individuals in seven states – Massachusetts, Utah, Washington, California, Virginia, and New York. All had been traveling internationally. All these confirmed cases in the United States were gay and bisexual men having sex with other men.

Monkeypox Treatment There are no approved medical treatments for Monkeypox. However, antiviral drugs, such as Tecovirimat (TPOXX), Cidofovir (Vistide), and Vaccinia Immune Globulin Intravenous (VIGIV), are approved to treat the smallpox virus and are effective in over 80% of the cases of Monkeypox. is a good source of information on this virus.


I think it is a colossal stretch to associate nine cases of Monkeypox in the United States with a headline that we need to act now to combat this new foe. Especially when all these monkeypox cases are associated with gay and bisexual men who traveled internationally to locations where this virus is endemic.

We are told that we should expect more cases as this virus spreads throughout the United States and the rest of the world. Would we have seen this headline and the warning to act now if we were not in the coronavirus pandemic? I believe not.

I think this is a typical response to anything that can potentially be a disaster, even when the likelihood is very close to zero. The sky is not falling.

Live Longer and Enjoy Life! – Red O’Laughlin –



Does Anyone Have Credibility Going into the Winter Months?

Who knows what lies past those mountains?

Over two years ago, in March of 2020, the worldwide death rate average for COVID-19 shot up exponentially – from under 100/day to almost 4,000/day. This week, the daily death average is under 2,000 for the first time since March 2020. The seven-day average of new cases is the lowest worldwide since the first week of November 2020.

Today’s Headline Immune protection is waning. The virus is adapting to be more contagious. Booster shots are necessary. Congress must approve new funding. Is any of this true?

No clinical studies have effectively assessed the immune protection afforded by naturally acquired immunity. Vaccine immunity disappears after six months, and a booster shot protection vanishes in less than four months. Yes, viruses mutate. Sometimes they get more deadly, and sometimes they do not.

We have seen the Omicron variant (several of them) infect more people faster than earlier viral variants, but the death toll is significantly less. Omicron is more contagious, and at the same time, it is less lethal. Who knows when the next mutation will occur? No one!

Who knows if the next viral mutation will be more contagious or deadly? No one! Shouting it from the rooftops (or headlines) does not make it true.

United States Status Over one million Americans have died from coronavirus in the past two years. Over eighty million people have contracted the virus. That means that almost 99% of the people survived. One hundred seventy-five thousand Americans died in the first six months of the pandemic. There were no protections afforded other than hunkering down at home, masking up, and social distancing.

When the first COVID-19 vaccines were released in December 2020, the total pandemic deaths exceeded 300,000. The first pandemic year produced over 400,000 deaths from this virus. Six months after vaccines were available, the total death toll from the pandemic virus exceeded 600,000. Since then, in June 2021, less than 400,000 Americans have died.

Did the vaccine help? I believe so. Did naturally acquired immunity help? Absolutely! However, what is still working today? Unfortunately, it is not the vaccine shots from early 2021.

Vaccine Effectiveness breakthrough is used to describe a condition happening that should not have occurred regarding the protections afforded by COVID-19 vaccines. Yesterday, an article from ABC News stated that breakthrough deaths make up a larger portion of deaths from the pandemic virus.

Eight months after COVID-19 vaccine shots were authorized for public use, just under 20% of the deaths occurred among those vaccinated. Six months later, the percentage more than doubled. Booster shots were available in September of 2021. Breakthrough deaths rose from one percent to twenty-five percent in five months for those fully vaccinated and boosted.

Over ninety percent of older Americans (over 65) have had both vaccine shots, and nearly seven out of ten have had their booster shots. Yet almost three out of four COVID-19 deaths were from this group of senior Americans. And overall, half the people eligible for booster shots have elected not to get them. Why? I cannot explain it.

Conclusion Who do you believe when it comes to forecasting the future of pandemic life? One hundred thirty-seven new COVID-19 vaccines are in clinical trials. Another 194 vaccines are in pre-clinical trials. Yes, vaccine development is still ongoing. Will one or more of these vaccines be more effective than the current batch? I hope so!

Twenty-five percent of Americans (over 80 million) have been assessed as having had coronavirus. Ninety-five percent of Americans have detectable levels of COVID-19 antibodies in their bodies.
America appears to have reasonable levels of protection from naturally acquired immunity and vaccine/booster shots. So why should I expect the pandemic virus to be worse than it is today by the end of this year? I do not.

I crunch the numbers periodically to see trends, and right now, the trends are falling to nearly pre-pandemic levels. Countries with zero tolerance are seeing their protections evaporate as their populations do not have naturally acquired immunity.

I do not know the effectiveness of their national vaccines over time. Why did so many people get infected so quickly if their vaccines were effective? Will I ever see a headline stating that there is a bright light at the end of the pandemic tunnel? Probably not!

Live Longer & Enjoy Life! – Red O’Laughin –


When Are We Going to Be Talking About a Post Pandemic World?

The post-pandemic world! Is it this way or that way?

It has been slightly over a month since I wrote about the pandemic virus. Unfortunately, headlines generally support another surge plowing through those few unvaccinated people – sooner than later.

The headline that attracted my attention today told us that most Americans have had coronavirus; however, the experts are predicting the next surge.

Is That True? is a source I often use to determine the current level of pandemic cases and deaths worldwide. Over 500,000,000 people have been infected, and the death rate is still around one percent – the virus survival rate is around 99%. So the big surge at the end of last year and the beginning of this year, along with a minor ripple in March, appears to be over.

Is there any indication that another surge is rapidly approaching? No, there is not. One could try to interpolate the likelihood of the next surge by viewing the frequency of previous waves of infection. January, April, August, and December were notable increases in cases worldwide last year.

Does that mean we will see four significant surges in 2022? Maybe, who really knows. As more and more people become infected, it should be less likely for new infections. But, for the sake of argument, let’s assume the experts are correct, and the next surge is just around the corner. Therefore, no post-pandemic world in view in 2022.

But, wait! Is it the number of cases or the number of deaths that really matter? If many people get infected and fewer people die, isn’t that a better measure of our future? The death rate is lower today than since March of 2020.

The big waves of deaths attributable to the pandemic occurred in April 2020, August 2020, December/January 2020/2021, May 2021, August 2021, and February 2022. Comparing the frequency of new cases to the resulting deaths from the pandemic virus indicates that fewer people are dying from the virus over the past year, no matter how many new cases are reported.

Maybe there is hope for a post-pandemic world in the next year? A committee of health advisors meet regularly to assess the pandemic. They declare whether the pandemic is still active or not. The World Health Organization accepted their opinion, and we continue to live in a pandemic world. Some nations (the Netherlands, Denmark, and the United Kingdom) have already declared the pandemic over.

However, a few reported cases do not mean the virus has been conquered. Look at Hong Kong, China, and other countries implementing zero-Covid tolerance and policies. Those protections lasted over a year. Then a viral variant began infecting millions nearly overnight.

How about those countries with previous high infection rates? The United States has almost sixty percent of adults and seventy-five percent of children with antibodies to the COVID-19 virus. Just before the Omicron outbreak in late 2021, only one-third of American adults had antibodies.

One viral variant infected a quarter of the population in just a couple of months. The CDC tells us that the antibodies last at least two years. The test results can distinguish between antibodies from the virus and the vaccine.

What is happening in the United States? The current new case trend is slightly upward. After over 800,000 daily cases in January 2022, the infection rate dropped below 30,000/day in just two months. Today’s seven-day-average rate is just over 60,000/day.

Deaths from the pandemic virus are also at nearly all-time lows. The summer of 2021 saw average daily deaths of around 250/day. The current average daily death rate is under 300/day. Considerable surges in new cases do not correlate with increasing numbers of deaths.

We still have doom and gloom living in predictions. One should be happy that pandemic deaths are nearly the lowest levels ever. Over half the American population has had the virus, and millions more vaccinated and boosted. Yet, the former White House

Coronavirus Response Task Force Coordinator tells us to expect new cases in the American south this summer and another surge in infections in the north this winter.

This forecast is based on South Africa’s frequency of viral surges – every four to six months. Yes, South Africa is experiencing an increase in new coronavirus cases.

Is South Africa a good indicator for the rest of the world? What is the antibody level of their country? How many are fully vaccinated and boosted? There are too many unknowns to pick a specific geographic area and make that the basis of what will happen in the United States.
Just under 80% of Americans have had one vaccine shot, and two-thirds are fully vaccinated.

However, does that really mean something since we know that vaccine protection gradually disappears after six months? I would put my money on the 60% of American adults who already had the virus to predict future infections better.

Of course, the experts are telling us that we need to change our terminology from ‘fully vaccinated’ to ‘up to date’ to include those with booster shots. Yet, less than one-third of Americans chose to get boosted. Is there a reason why?


There will always be experts predicting doom and gloom. It is their nature. The survival rate from the SARS-CoV-2 virus has historically been around 99%. The survival rate for older adults with health issues is 80-85%, depending on age.

I have always maintained that we must protect those most vulnerable to infection. Unfortunately, many factors prevented adequate protection in the early days of the pandemic. Those days have passed, and we know more about the virus.

Can a new, more deadly viral variant arrive on our doorsteps tomorrow? Absolutely. Can a new, far less lethal viral variant also arrive on our doorsteps tomorrow? Absolutely. Will a vaccine developed for a viral variant a year or two ago be effective against a new mutation of the virus? Most likely not. So, what can we do?

I preach awareness and education regarding health and wellness daily. What can you do to protect yourself from infection – any infection? Build up and maintain a robust immune system. Will it prevent you from becoming infected by the pandemic virus or other visiting viral cousins? No, but it will probably lessen any symptoms you might get. And you will most likely, over 99% likely survive any future bout with our pandemic virus.

And, the post-pandemic world should arrive much earlier than the doom and gloom experts predict, in my humble opinion. It will not occur everywhere at the same time, but it is closer than most of us think.

Live Longer & Enjoy Life! – Red O’Laughin –


Is the Hard-Line ‘Zero Infection’ Approach the Best Method?

Shanghai, China has locked down again due to the pandemic virus.

“Pay me now or pay me later, but pay me you will” was a famous 1970 Fram oil filter slogan. I believe that the same applies to our pandemic. But, unfortunately, hiding from the virus now and the virus will find you later is what we see in many places.

Vaccine Protection Declining,COV2.,to%2061.5)%20at%205%20months. It has been known for many months that the effectiveness of the pandemic vaccines declines over time. Six months after the second shot, the vaccine’s effectiveness is close to 50% of its original protection.

Many people believed the vaccines would work. When breakthrough cases, hospitalizations, and deaths increased, boosters were made available. Yet, many chose not to get boosted. Why?

When polled, the two primary reasons were convenience and belief it would work. If the vaccines do not work, why bother with the booster shot.

Omicron Variants The current plaque of new cases worldwide appears to be one of the two primary Omicron variants – the BA 2. The World Health Organization stated that the BA 2 variant is slightly different in genetic sequence but not enough to classify it as a new variant.

Transmissibility of the Omicron BA 2 is slightly less than the BA 1. Yet, countries that survived the earlier variants by extremely rigid restrictions are seeing astronomically high case rates. On the other hand, death rates are meager.

Locking Down (Again) Shanghai, the largest city in China with over twenty-six million, is locked down again. Yesterday, health officials reported nearly 440 new cases. In twenty-four hours, testing revealed over 7,500 asymptomatic cases of the BA 2 variant.

Shanghai began another lockdown last week – a two-stage process that returned to the early pandemic regulations. The city endured over two months of a rigidly enforced complete shutdown early in the pandemic. As a result, the citizens are not as compliant as a year ago.

Other Countries and BA 2 The country reporting the highest new case rate is South Korea, with over 250,000 per day. Even at that level, just over 300 per day are dying from the virus. France, Germany, Italy, Vietnam, Australia, and Japan are seeing high new case rates – in some cases, the highest since the pandemic started.

Deaths from the pandemic virus are highest in Russia, South Korea, Germany, the United States, Italy, and Brazil. The death rates are extremely low for the percent of new infections. Most countries have a 99% or higher survival rate from COVID-19.

Zero-COVID Strategy Failing?,contain%20new%20outbreaks%20before%20they. According to Wikipedia, Zero-COVID Strategy (also known as COVID Zero) is a public health policy to finding, testing, tracing, isolating, and supporting to maximize suppression of the virus.

Several countries in the western Pacific adopted this policy and kept coronavirus from spreading. New cases and deaths were rarely above the low double digits. Some countries were able to record zero (or very low single digits) new cases for an extended period, such as New Zealand.

For over a year, New Zealand was a shining example of how to shut down the spread of the pandemic virus. In less than a month, new cases shot up to over 20,000/day ( The death rate in New Zealand, which had been almost zero, has climbed to the low double digits.

Infections & Restrictions Shutting businesses down, restricting travel into and out of the country, quarantines, and other measures are not working, especially with the latest variant of Omicron. Let one person into the country with the virus, and new caseloads explode.

It is hard to put the genie back in the bottle once it has escaped. Public support for such restrictive measures is also waning. Mass testing is ongoing along with make-shift hospitals and quarantine centers. China claims that it controlled the initial pandemic, and for almost two years, that have been near zero new cases until recently.

China’s travel restrictions are strictly controlled and monitored. Screening is done immediately, and mandatory two-week quarantines are required for new visitors. In addition, regular testing is done by neighborhoods, and those testing positive are evicted, quarantined, and possibly new lockdowns instituted in those areas.

All non-essential businesses have been shut down. Public transportation is suspended, along with most vehicular traffic is banned. Schools have been closed. Self-test kits are available across the country. Those testing positive with the self-test kits must have a PCR test for confirmation.


Were the Alpha, Beta, and Delta variants easier to contain? Probably not. However, when you can control who goes where and when the spread of disease is limited. Widespread testing also facilitates knowing that the control measures are working. Quarantines were established initially to take the load off healthcare facilities.

With a 99% survival rate, healthcare treatment is a numbers game. If one thousand people become infected today, less than one hundred will need hospital care, and ten may die from the virus. When the daily numbers approach 250,000/day, healthcare facilities may not be able to care for those in need.

The data I researched surprised me the most was the ratio of asymptomatic new cases to those with symptoms. A ratio of nearly 18:1 is being recorded in Shanghai for the BA 2 variant. Eighteen people are infected with no symptoms for one who has the virus with symptoms. That is a staggering number. No wonder so many people are getting infected and infecting others.

Couple a very high transmission rate for COVID-19 (the Omicron variant) with populations that have been held in check (even with vaccinations), the wildfire of new cases is bound to erupt as the restrictions fail to protect against infection.

Pay me now or pay me later, but pay me you will apply to our pandemic. Protect people with the harshest restrictions, and the bug will bite you in the end when you are not prepared for it. Are we scared of a 99% survivability rate for this virus? Or are we unwilling to protect those genuinely vulnerable and allow the rest of the citizens to take that 99:1 risk?

The risk is much lower for those under 50 years of age. Seasonal influenza kills tens of thousands of people in a bad flu season and is currently the number nine cause of death in the United States. Would the numbers be similar for the pandemic virus if the most vulnerable were well protected?

Live Longer & Enjoy Life! – Red O’Laughlin –

Can Infrared Light Therapy Improve Memory Performance in Those With and Without Dementia?

Light therapy to improve brain function may also help those with dementia.

Last summer, I wrote about a light and sound therapy to help those with Alzheimer’s disease. Here is an excerpt from that article.

Modulated Light & Sound Alzheimer’s patients were exposed to a rhythmic brain pattern focused on gamma rays, the fast brain activity. It is where we learn, process, and remember.

Scientists found reductions in amyloid plaque by using visible light flashes at 40 Hz manipulated gamma brain waves. The testing was successful on laboratory animals, and human testing began using synchronized audio with the flashing light. In addition, a placebo white noise and random light flashes were used as a placebo.

Results After three months of human studies using light and sound, the brains of AD patients showed improvement – brain degeneration slowed. No side effects were noted.

A second study was done for six months with about five times the number of AD patients. A similar placebo treatment was incorporated into the test. The placebo group in both studies showed no improvement in the progression of AD. This second study noted a 65% improvement in disease progression.

Another leap forward in the battle against dementia has been achieved using infrared light. Late last year, a Durham University study showed that motor function and processing skills improved with light therapy.

Transcranial PBM-T (Photobiomodulation therapy) uses an infrared wavelength at 2068 nanometers twice daily for six minutes each time. The pilot study was very promising, and it is believed that the memory performance achieved could be beneficial to both those with and without dementia. The study was published in the Photobiomodulation, Photomedicine and Laser Surgery Journal

A control group and a placebo group were tested for one month. Significant improvement was noted in the control group. Motor function, memory, and brain processing speed improved. A helmet delivered infrared light directly into the cranium. It is believed that dying brain cells are regenerated into fully functional cells.


I have written over 40 articles on Alzheimer’s and other neurodegenerative diseases. In the past month, new studies have revealed potential new ways to diagnose or treat dementia. This study looks promising, and I hope that the follow-on clinical studies prove successful in treating Alzheimer’s and other related diseases.

Live Longer & Enjoy Life! – Red O’Laughlin –


Five Natural Options to Reduce Cholesterol in Fifty Days

A cheeseburger and French fries are not recommended when you have high cholesterol.

Cholesterol is an exciting topic. Our bodies make it. Nearly every cell in our bodies needs it. Statin drugs to treat cholesterol shuts down the body’s production of it.

Personal Story

For most of my life, my total cholesterol ran in the range of 104-114 mg/dl. I was eating double cheeseburgers (triples at one point in my early life), sausage and cheese omelets, and other foods that typically cause cholesterol levels to increase. Why did my total cholesterol remain so low?

I asked many flight surgeons and an occasional family doctor, and no one could tell me at what point low total cholesterol could become a problem. Unfortunately, there is little definitive information on how low is too low regarding total cholesterol with internet searches today. Regardless, near the end of my sixteen years of flying, I found a flight surgeon who told me he would worry if any of his patient’s total cholesterol dropped below 90 mg/dl.


Our bodies make cholesterol, and the foods we eat add cholesterol. There is a balance between the body’s production and food-supplied cholesterol. When you are no longer eating high cholesterol-producing foods, your body makes more. Conversely, when you eat more foods that increase cholesterol, your body produces less.

For most of us, cholesterol production and dietary cholesterol intake are not a problem. Yet, many doctors fear that when total cholesterol goes over 200 mg/dl, they must take action to reduce it. Yes, the evidence points to increased risk of more plaque in the heart valves and arteries, increased risk of high blood pressure, and an increased risk of other cardiovascular diseases.


Plaque builds up in the heart valves and arteries over time. It is made up primarily of oxidized fat (cholesterol) and calcium. Calcium forms plaque when the body does not have enough vitamin K2 to cause calcium to go into the bones. Oxidized cholesterol is formed by eating commercially fried foods, excess polyunsaturated fatty acids, and smoking.

Cholesterol Reduction Five lifestyle changes have been shown to reduce cholesterol. Eat more foods high in fiber -fruits and vegetables. Minimize unhealthy fats in your food selections. Eat fewer refined grains (white flour), stop smoking, and exercise more.

Other things to consider? Increase omega-3 fatty acids and reduce omega-6 fatty acids. Avoid trans-fat. Supplement with more soluble fiber. Maintain a healthy weight. And drink alcohol in moderation.


Researchers tell us that for every ten percent drop in your cholesterol level, your heart attack risk drops by around 25%.

The medical profession concentrates on cholesterol numbers rather than ratios. Doctors usually give their patients the total cholesterol number. You need to know all the cholesterol numbers, not just the total.

The HDL cholesterol ratio and total cholesterol are more critical than the total cholesterol by itself. The ratio of total cholesterol divided by HDL cholesterol should be less than 5.0, with an ideal ratio of around 3.5.

When your total cholesterol is 200 mg/dl and your HDL is 35 mg/dl, your ratio is 5.7 – something to be concerned about. When your total cholesterol is 200 mg/dl, and your HDL is 60 mg/dl your ratio is 3.3 mg/dl – almost ideal. The same total cholesterol number can mean two different things based on the HDL levels.

Live Longer & Enjoy Life! – Red O’Laughlin –


Eight Natural Options to Remedies That Reduce Headache Pain

Headaches! Some natural treatments work as well as drugs.

Over forty million Americans get headaches each year. Eight million of them will have to visit a doctor’s office. The most common type is the tension headache. The other two common types of headaches are migraines and clusters.

There are many drugs used to treat headaches. This link lists the most.

Natural Options

Drink Water

Headaches can be caused by dehydration.,and%20taking%20pain%20relief%20medication.

Relaxation Techniques

Tension headaches may be treated with several types of relaxation techniques.


Low levels of magnesium are also known to cause headaches.,transmitting%20chemicals%20in%20the%20brain.

Ginger Tea

Inflammation is another known cause of headaches. An anti-inflammatory such as ginger tea is known to work well.

Hot or Cold Compress

It is an individual’s choice to use hot or cold compresses. Place it on your forehead, temples, or back of your neck. I prefer a very hot shower to soak my neck, shoulder, and back muscles.,may%20have%20a%20similar%20effect.


Traditional treatment for many ailments is butterbur, Petasites hybridus.

Vitamin B2

A deficiency in the B vitamins can cause headaches. For example, a riboflavin deficiency (vitamin B2) appears to be more headache-inducing than other B vitamins.,next%20two%20months%2C%20researchers%20said.

Turn Off the Screen

Blue light can create eye strain and headaches. I bought a new computer monitor a while back and immediately had eye problems and headaches – within ten or twenty minutes. I bought a pair of blue-light filter glasses, and I can spend hours without any health issues. When you suspect that your electronic device might contribute to your headache, take a fifteen or twenty-minute break.


There are many causes of headaches. Treating a pathway that is not the cause of your headache may have no effect. For example, there may also be more than one cause – stress/muscle tension and blue light. Assess your life to determine what lifestyle changes might be needed. This link is a good one to review potential causes of headaches.

See your doctor when your headaches are increasing in frequency or severity or are interfering with your daily interactions.

Live Longer & Enjoy Life! – Red O’Laughlin – RedOLaughlin


Six Ways to Lower Blood Pressure Without Drugs

When was the last time you took your blood pressure? I take mine daily.

Many things are known to cause high blood pressure. In some cases, it is probably caused by a combination of factors. Drugs treat a specific pathway. Over time, drug dosage or the type of drug is changed because it may no longer be effective.

What are typical causes of high blood pressure? Smoking, obesity, too much salt, too much alcohol, unmanaged stress, old age, genetics, and more are part of the list.

Dangers of High Blood Pressure This is a good link on high blood pressure. Complications from high blood pressure could be a heart attack or stroke, aneurysm, heart failure, weakened blood vessels in the kidney, thickened blood vessels in the eyes, metabolic syndrome, memory problems, and maybe even vascular dementia.

The cost of a blood pressure monitor has fallen a lot in recent years. I did a quick Google search and found several under $20. It is a good insurance policy to get a blood pressure monitor and use it often. Record your times and blood pressure readings. Take this information to your doctor when you have a problem or at your annual physical exam.

Drug Options One method of lowering blood pressure is to inhibit angiotensin-converting enzymes (ACE). Nearly half of the prescription drugs used to control blood pressure are ACE inhibitors.

Side effects of ACE inhibitors used to control blood pressure include a dry cough, hyperkalemia (increased potassium levels in the blood), fatigue, dizziness, nausea, headaches, and loss of taste. Angioedema or swelling of the airway happens rarely. There are three groups of people who should avoid ACE inhibitors – those who are pregnant, those who have severe kidney failure, and those with allergic reactions to ACE inhibitors should not use them.

Natural ACE Inhibitor Options


Grape Seed Extract

Pomegranate Juice,and%20reduces%20systolic%20blood%20pressure.

Indian Gooseberry and

Mushrooms (Lion’s mane, shiitake, maitake, and reishi),blood%20pressure%20increase%20in%20hypertension and

Whey Protein and


There are other natural options to treat high blood pressure. Unfortunately, doctors cannot prescribe any of the above since they are foods and are not approved by the FDA to treat anything. However, you can talk to your physician and tell him that you want to try one or more of these natural options and work a plan that will align with any current drugs you currently take.

If not on a prescription drug, I suggest getting your doctor’s approval to take one or more natural options, regularly monitor your blood pressure, and report back to the doctor within an agreed-upon schedule. High blood pressure is not something to ignore.

My personal experience with high blood pressure when I flew in the military was that if I kept my weight in check and exercised regularly, I never flirted with high blood pressure. However, if I gained weight over the year and slacked on my exercise, I would tend towards more elevated blood pressure. There are natural options to control blood pressure.

Live Longer & Enjoy Life! – Red O’Laughlin –